Topic
Medication & Treatment
Why treatment depends on subtype — from no medication at all to sulfonylureas or insulin.
Why Your Result Changes Treatment
A genetic diagnosis in monogenic diabetes is not academic at all. It can move someone off insulin onto a tablet, or off treatment entirely.
Coming Off Insulin After a Diagnosis
Most people with HNF1A or HNF4A-MODY change treatment after diagnosis, and some stop insulin entirely. Here is what actually predicts success.
Low-Dose Sulfonylureas
An old and inexpensive tablet is the treatment of choice for the two commonest Indian MODY subtypes — and low doses are very much the point.
When No Treatment Is Right
In GCK-MODY, glucose-lowering treatment is generally ineffective and stopping it is often correct. It is also never a self-directed decision.
When Insulin Is Still Needed
A monogenic diagnosis does not always mean coming off insulin at all. Here are the situations in which insulin remains the right treatment.